Benzeneacetic acid, 2-bromo-α-oxo-
2-(2-Bromophenyl)-2-oxoacetic acid
CAS: 26767-16-8
Molecular Formula: C8H5BrO3
Benzeneacetic acid, 2-bromo-α-oxo- - Names and Identifiers
Benzeneacetic acid, 2-bromo-α-oxo- - Physico-chemical Properties
| Molecular Formula | C8H5BrO3 |
| Molar Mass | 229.03 |
| Density | 1.738±0.06 g/cm3(Predicted) |
| Melting Point | 104-107 °C |
| Boling Point | 330.5±34.0 °C(Predicted) |
| pKa | 1.91±0.54(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Irritant |
| MDL | MFCD00463413 |
Benzeneacetic acid, 2-bromo-α-oxo- - Risk and Safety
| Hazard Class | IRRITANT |
Benzeneacetic acid, 2-bromo-α-oxo- - Introduction
2-(2-Bromophenyl)-2-oxoacetic acid is an organic compound with the chemical formula C8H7BrO3.
Nature:
-Appearance: Colorless solid
-Melting point: about 130-135 degrees Celsius
-Solubility: Soluble in ethanol, chloroform and dichloromethane, slightly soluble in water
Use:
- 2-(2-Bromophenyl)-2-oxoacetic acid is an important intermediate in organic synthesis and can be used to synthesize other compounds.
-It can be used as a synthetic raw material for drugs and pesticides.
Preparation Method:
It can be prepared by the following steps:
1.2-bromobenzoic acid is reacted with phosphoryl bromide in sodium hydroxide solution to obtain 2-(2-bromophenyl) acetic acid.
2. esterification of 2-(2-bromophenyl) acetic acid with 2-oxopropionyl chloride in alkaline solution to give 2-(2-Bromophenyl)-2-oxoacetic acid.
Safety Information:
- 2-(2-Bromophenyl)-2-oxoacetic acid is an organic compound that is potentially dangerous.
-Appropriate laboratory safety measures need to be taken when handling it, including wearing protective gloves, goggles and laboratory coats.
-Avoid inhaling its powder or vapor, avoiding skin contact and swallowing.
-When using it should maintain a well-ventilated laboratory environment.
Nature:
-Appearance: Colorless solid
-Melting point: about 130-135 degrees Celsius
-Solubility: Soluble in ethanol, chloroform and dichloromethane, slightly soluble in water
Use:
- 2-(2-Bromophenyl)-2-oxoacetic acid is an important intermediate in organic synthesis and can be used to synthesize other compounds.
-It can be used as a synthetic raw material for drugs and pesticides.
Preparation Method:
It can be prepared by the following steps:
1.2-bromobenzoic acid is reacted with phosphoryl bromide in sodium hydroxide solution to obtain 2-(2-bromophenyl) acetic acid.
2. esterification of 2-(2-bromophenyl) acetic acid with 2-oxopropionyl chloride in alkaline solution to give 2-(2-Bromophenyl)-2-oxoacetic acid.
Safety Information:
- 2-(2-Bromophenyl)-2-oxoacetic acid is an organic compound that is potentially dangerous.
-Appropriate laboratory safety measures need to be taken when handling it, including wearing protective gloves, goggles and laboratory coats.
-Avoid inhaling its powder or vapor, avoiding skin contact and swallowing.
-When using it should maintain a well-ventilated laboratory environment.
Last Update：2024-04-09 02:00:56
